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Evaluation of Arecoline Hydrobromide Toxicity after a 14-Day Repeated Oral Administration in Wistar Rats
A subchronic toxicity test was conducted in rats on the basis of a previous acute toxicity test to evaluate the safety of arecoline hydrobromide (Ah), to systematically study its pharmacological effects and to provide experimental support for a safe clinical dose. Eighty rats were randomly divided i...
Autores principales: | Wei, Xiaojuan, Zhang, Jiyu, Niu, Jianrong, Zhou, Xuzheng, Li, Jianyong, Li, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399984/ https://www.ncbi.nlm.nih.gov/pubmed/25880067 http://dx.doi.org/10.1371/journal.pone.0120165 |
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