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Dynamic Modulation of Thymidylate Synthase Gene Expression and Fluorouracil Sensitivity in Human Colorectal Cancer Cells

Biomarkers have revolutionized cancer chemotherapy. However, many biomarker candidates are still in debate. In addition to clinical studies, a priori experimental approaches are needed. Thymidylate synthase (TS) expression is a long-standing candidate as a biomarker for 5-fluorouracil (5-FU) treatme...

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Detalles Bibliográficos
Autores principales:	Wakasa, Kentaro, Kawabata, Rumi, Nakao, Seiki, Hattori, Hiroyoshi, Taguchi, Kenichi, Uchida, Junji, Yamanaka, Takeharu, Maehara, Yoshihiko, Fukushima, Masakazu, Oda, Shinya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400010/ https://www.ncbi.nlm.nih.gov/pubmed/25881233 http://dx.doi.org/10.1371/journal.pone.0123076

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