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IMPIPS: The Immune Protection-Inducing Protein Structure Concept in the Search for Steric-Electron and Topochemical Principles for Complete Fully-Protective Chemically Synthesised Vaccine Development
Determining immune protection-inducing protein structures (IMPIPS) involves defining the stereo-electron and topochemical characteristics which are essential in MHC-p-TCR complex formation. Modified high activity binding peptides (mHABP) were thus synthesised to produce a large panel of IMPIPS measu...
Autores principales: | Patarroyo, Manuel Elkin, Bermúdez, Adriana, Alba, Martha Patricia, Vanegas, Magnolia, Moreno-Vranich, Armando, Poloche, Luis Antonio, Patarroyo, Manuel Alfonso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400017/ https://www.ncbi.nlm.nih.gov/pubmed/25879751 http://dx.doi.org/10.1371/journal.pone.0123249 |
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