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Trehalose-Mediated Autophagy Impairs the Anti-Viral Function of Human Primary Airway Epithelial Cells

Human rhinovirus (HRV) is the most common cause of acute exacerbations of chronic lung diseases including asthma. Impaired anti-viral IFN-λ1 production and increased HRV replication in human asthmatic airway epithelial cells may be one of the underlying mechanisms leading to asthma exacerbations. In...

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Detalles Bibliográficos
Autores principales: Wu, Qun, Jiang, Di, Huang, Chunjian, van Dyk, Linda F., Li, Liwu, Chu, Hong Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400043/
https://www.ncbi.nlm.nih.gov/pubmed/25879848
http://dx.doi.org/10.1371/journal.pone.0124524

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