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Retinoid X Receptor α Overexpression Alleviates Mitochondrial Dysfunction-induced Insulin Resistance through Transcriptional Regulation of Insulin Receptor Substrate 1
Mitochondrial dysfunction is associated with insulin resistance and diabetes. We previously showed that retinoid X receptor α (RXRα) played an important role in transcriptional regulation of oxidative phosphorylation (OXPHOS) genes in cells with mitochondrial dysfunction caused by mitochondrial DNA...
Autores principales: | Lee, Seung Eun, Koo, Young Do, Lee, Ji Seon, Kwak, Soo Heon, Jung, Hye Seung, Cho, Young Min, Park, Young Joo, Chung, Sung Soo, Park, Kyong Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400311/ https://www.ncbi.nlm.nih.gov/pubmed/25728751 http://dx.doi.org/10.14348/molcells.2015.2280 |
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