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A Novel Pyruvate Kinase M2 Activator Compound that Suppresses Lung Cancer Cell Viability under Hypoxia

Pyruvate kinase M2 isoform (PKM2), a rate-limiting enzyme in the final step of glycolysis, is known to be associated with the metabolic rewiring of cancer cells, and considered an important cancer therapeutic target. Herein, we report a novel PKM2 activator, PA-12, which was identified via the molec...

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Detalles Bibliográficos
Autores principales:	Kim, Dong Joon, Park, Young Soo, Kim, Nam Doo, Min, Sang Hyun, You, Yeon-Mi, Jung, Yuri, Koo, Han, Noh, Hanmi, Kim, Jung-Ae, Park, Kyung Chan, Yeom, Young Il
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400313/ https://www.ncbi.nlm.nih.gov/pubmed/25813626 http://dx.doi.org/10.14348/molcells.2015.2314

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