Recognition of Cytosolic DNA Attenuates Glucose Metabolism and Induces AMPK Mediated Energy Stress Response

Both viral infection and DNA transfection expose single-stranded or double-stranded DNA to the cytoplasm of mammalian cells. Recognition of cytosolic DNA activates a series of cellular responses, including induction of pro-inflammatory genes such as type I interferon through the well-known cGAS-STIN...

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Detalles Bibliográficos
Autores principales: Zheng, Min, Xie, Linna, Liang, Yaoji, Wu, Suqin, Xu, Huijuan, Zhang, Yuedong, Liu, Hekun, Lin, Dexin, Han, Jiahuai, Lu, Kunping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400389/
https://www.ncbi.nlm.nih.gov/pubmed/25892965
http://dx.doi.org/10.7150/ijbs.10945

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