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Tamoxifen Inhibits ER-negative Breast Cancer Cell Invasion and Metastasis by Accelerating Twist1 Degradation

Twist1 is a transcription factor driving epithelial-mesenchymal transition, invasion and metastasis of breast cancer cells. Mice with germ-line Twist1 knockout are embryonic lethal, while adult mice with inducible Twist1 knockout have no obvious health problems, suggesting that Twist1 is a viable th...

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Detalles Bibliográficos
Autores principales:	Ma, Gang, He, Jianjun, Yu, Yang, Xu, Yixiang, Yu, Xiaobin, Martinez, Jarrod, Lonard, David M., Xu, Jianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400392/ https://www.ncbi.nlm.nih.gov/pubmed/25892968 http://dx.doi.org/10.7150/ijbs.11380

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