Epstein–Barr virus-associated nephrotic syndrome

Acute infection with Epstein–Barr virus (EBV) causes fever, fatigue and pharyngitis. Renal involvement in systemic EBV infections typically manifests as acute tubular necrosis or tubulointerstitial nephritis. Rarely, EBV infection causes nephrotic syndrome due to minimal change disease. A 22-year-ol...

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Autores principales: Mikhalkova, Deana, Khanna, Sahil, Vaidya, Rakhee, Sethi, Sanjeev, Hogan, Marie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Clinical Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400449/
https://www.ncbi.nlm.nih.gov/pubmed/26069749
http://dx.doi.org/10.1093/ndtplus/sfr119
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author Mikhalkova, Deana
Khanna, Sahil
Vaidya, Rakhee
Sethi, Sanjeev
Hogan, Marie C.
author_facet Mikhalkova, Deana
Khanna, Sahil
Vaidya, Rakhee
Sethi, Sanjeev
Hogan, Marie C.
author_sort Mikhalkova, Deana
collection PubMed
description Acute infection with Epstein–Barr virus (EBV) causes fever, fatigue and pharyngitis. Renal involvement in systemic EBV infections typically manifests as acute tubular necrosis or tubulointerstitial nephritis. Rarely, EBV infection causes nephrotic syndrome due to minimal change disease. A 22-year-old male with infectious mononucleosis (IM) presented with nephrotic syndrome. Renal biopsy showed minimal change disease with diffuse foot process effacement of the podocytes. Treatment with methylprednisone led to rapid and complete clinical remission. Minimal change nephropathy is a very rare manifestation of EBV infection and should be considered in patients with IM and proteinuria.
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spelling pubmed-44004492015-06-11 Epstein–Barr virus-associated nephrotic syndrome Mikhalkova, Deana Khanna, Sahil Vaidya, Rakhee Sethi, Sanjeev Hogan, Marie C. Clin Kidney J Clinical Cases Acute infection with Epstein–Barr virus (EBV) causes fever, fatigue and pharyngitis. Renal involvement in systemic EBV infections typically manifests as acute tubular necrosis or tubulointerstitial nephritis. Rarely, EBV infection causes nephrotic syndrome due to minimal change disease. A 22-year-old male with infectious mononucleosis (IM) presented with nephrotic syndrome. Renal biopsy showed minimal change disease with diffuse foot process effacement of the podocytes. Treatment with methylprednisone led to rapid and complete clinical remission. Minimal change nephropathy is a very rare manifestation of EBV infection and should be considered in patients with IM and proteinuria. Oxford University Press 2012-02 /pmc/articles/PMC4400449/ /pubmed/26069749 http://dx.doi.org/10.1093/ndtplus/sfr119 Text en © The Author 2012. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Clinical Cases
Mikhalkova, Deana
Khanna, Sahil
Vaidya, Rakhee
Sethi, Sanjeev
Hogan, Marie C.
Epstein–Barr virus-associated nephrotic syndrome
title Epstein–Barr virus-associated nephrotic syndrome
title_full Epstein–Barr virus-associated nephrotic syndrome
title_fullStr Epstein–Barr virus-associated nephrotic syndrome
title_full_unstemmed Epstein–Barr virus-associated nephrotic syndrome
title_short Epstein–Barr virus-associated nephrotic syndrome
title_sort epstein–barr virus-associated nephrotic syndrome
topic Clinical Cases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400449/
https://www.ncbi.nlm.nih.gov/pubmed/26069749
http://dx.doi.org/10.1093/ndtplus/sfr119
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