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Eculizumab in atypical haemolytic–uraemic syndrome allows cessation of plasma exchange and dialysis
Disorders in complement regulation are a major cause of atypical haemolytic–uraemic syndrome (aHUS). Eculizumab, a monoclonal antibody targeting complement C5 and blocking the terminal complement cascade, should theoretically be useful in this disease, particularly when associated with specific comp...
Autores principales: | Kim, Jon Jin, Waller, Simon C., Reid, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400463/ https://www.ncbi.nlm.nih.gov/pubmed/26069744 http://dx.doi.org/10.1093/ndtplus/sfr174 |
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