Membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis

We describe a 61-year-old woman with acute kidney injury, nephrotic range proteinuria and hematuria. Kidney biopsy showed membranous glomerulopathy (MG) with superimposed pauci-immune necrotizing crescentic glomerulonephritis (PNCGN). Coexistent MG and PNCGN is a rare occurrence. The diagnosis of su...

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Autores principales: Fatima, Huma, Siew, Edward D., Dwyer, Jamie P., Paueksakon, Paisit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Clinical Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400567/
https://www.ncbi.nlm.nih.gov/pubmed/26069808
http://dx.doi.org/10.1093/ckj/sfs145
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author Fatima, Huma
Siew, Edward D.
Dwyer, Jamie P.
Paueksakon, Paisit
author_facet Fatima, Huma
Siew, Edward D.
Dwyer, Jamie P.
Paueksakon, Paisit
author_sort Fatima, Huma
collection PubMed
description We describe a 61-year-old woman with acute kidney injury, nephrotic range proteinuria and hematuria. Kidney biopsy showed membranous glomerulopathy (MG) with superimposed pauci-immune necrotizing crescentic glomerulonephritis (PNCGN). Coexistent MG and PNCGN is a rare occurrence. The diagnosis of such an exceptionally rare combination relies on the combination of renal biopsy findings and serologic testing. We also review previous reported cases and discuss possible pathogenesis of this rare dual glomerulopathy.
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spelling pubmed-44005672015-06-11 Membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis Fatima, Huma Siew, Edward D. Dwyer, Jamie P. Paueksakon, Paisit Clin Kidney J Clinical Cases We describe a 61-year-old woman with acute kidney injury, nephrotic range proteinuria and hematuria. Kidney biopsy showed membranous glomerulopathy (MG) with superimposed pauci-immune necrotizing crescentic glomerulonephritis (PNCGN). Coexistent MG and PNCGN is a rare occurrence. The diagnosis of such an exceptionally rare combination relies on the combination of renal biopsy findings and serologic testing. We also review previous reported cases and discuss possible pathogenesis of this rare dual glomerulopathy. Oxford University Press 2012-12 /pmc/articles/PMC4400567/ /pubmed/26069808 http://dx.doi.org/10.1093/ckj/sfs145 Text en © The Author 2012. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please email: journals.permissions@oup.com. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Clinical Cases
Fatima, Huma
Siew, Edward D.
Dwyer, Jamie P.
Paueksakon, Paisit
Membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis
title Membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis
title_full Membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis
title_fullStr Membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis
title_full_unstemmed Membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis
title_short Membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis
title_sort membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis
topic Clinical Cases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400567/
https://www.ncbi.nlm.nih.gov/pubmed/26069808
http://dx.doi.org/10.1093/ckj/sfs145
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AT dwyerjamiep membranousglomerulopathywithsuperimposedpauciimmunenecrotizingcrescenticglomerulonephritis
AT paueksakonpaisit membranousglomerulopathywithsuperimposedpauciimmunenecrotizingcrescenticglomerulonephritis

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