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Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion
The role of specific phospholipids (PLs) in lipid transport has been difficult to assess due to an inability to selectively manipulate membrane composition in vivo. Here we show that the phospholipid remodeling enzyme lysophosphatidylcholine acyltransferase 3 (Lpcat3) is a critical determinant of tr...
Autores principales: | Rong, Xin, Wang, Bo, Dunham, Merlow M, Hedde, Per Niklas, Wong, Jinny S, Gratton, Enrico, Young, Stephen G, Ford, David A, Tontonoz, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400582/ https://www.ncbi.nlm.nih.gov/pubmed/25806685 http://dx.doi.org/10.7554/eLife.06557 |
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