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Efficient retina formation requires suppression of both Activin and BMP signaling pathways in pluripotent cells
Retina formation requires the correct spatiotemporal patterning of key regulatory factors. While it is known that repression of several signaling pathways lead to specification of retinal fates, addition of only Noggin, a known BMP antagonist, can convert pluripotent Xenopus laevis animal cap cells...
Autores principales: | Wong, Kimberly A., Trembley, Michael, Abd Wahab, Syafiq, Viczian, Andrea S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400599/ https://www.ncbi.nlm.nih.gov/pubmed/25750435 http://dx.doi.org/10.1242/bio.20149977 |
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