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Efficient retina formation requires suppression of both Activin and BMP signaling pathways in pluripotent cells

Retina formation requires the correct spatiotemporal patterning of key regulatory factors. While it is known that repression of several signaling pathways lead to specification of retinal fates, addition of only Noggin, a known BMP antagonist, can convert pluripotent Xenopus laevis animal cap cells...

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Detalles Bibliográficos
Autores principales: Wong, Kimberly A., Trembley, Michael, Abd Wahab, Syafiq, Viczian, Andrea S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400599/
https://www.ncbi.nlm.nih.gov/pubmed/25750435
http://dx.doi.org/10.1242/bio.20149977

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