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γ-Secretase: a multifaceted regulator of angiogenesis

Physiological angiogenesis is essential for development, homeostasis and tissue repair but pathological neovascularization is a major feature of tumours, rheumatoid arthritis and ocular complications. Studies over the last decade have identified γ-secretase, a presenilin-dependent protease, as a key...

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Detalles Bibliográficos
Autores principales: Boulton, Michael E, Cai, Jun, Grant, Maria B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401127/
https://www.ncbi.nlm.nih.gov/pubmed/18266961
http://dx.doi.org/10.1111/j.1582-4934.2008.00274.x