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Blocking translocation of cell surface molecules from the ER to the cell surface by intracellular antibodies targeted to the ER
Intracellular antibodies (intrabodies) constitute a potent tool to neutralize the function of target proteins inside specific cell compartments (cytosol, nucleus, mitochondria and ER). The intrabody technology is an attractive alternative to the generation of gene-targeted knockout animals and compl...
Autor principal: | Böldicke, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401220/ https://www.ncbi.nlm.nih.gov/pubmed/17367501 http://dx.doi.org/10.1111/j.1582-4934.2007.00002.x |
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