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The misuse and abuse of statistics in biomedical research
Statistics are the primary tools for assessing relationships and evaluating study questions. Unfortunately, these tools are often misused, either inadvertently because of ignorance or lack of planning, or conspicuously to achieve a specified result. Data abuses include the incorrect application of s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Croatian Society of Medical Biochemistry and Laboratory Medicine
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401313/ https://www.ncbi.nlm.nih.gov/pubmed/25672462 http://dx.doi.org/10.11613/BM.2015.001 |
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author | Thiese, Matthew S. Arnold, Zachary C. Walker, Skyler D. |
author_facet | Thiese, Matthew S. Arnold, Zachary C. Walker, Skyler D. |
author_sort | Thiese, Matthew S. |
collection | PubMed |
description | Statistics are the primary tools for assessing relationships and evaluating study questions. Unfortunately, these tools are often misused, either inadvertently because of ignorance or lack of planning, or conspicuously to achieve a specified result. Data abuses include the incorrect application of statistical tests, lack of transparency and disclosure about decisions that are made, incomplete or incorrect multivariate model building, or exclusion of outliers. Individually, each of these actions may completely invalidate a study, and often studies are victim to more than one offense. Increasingly there are tools and guidance for researchers to look to, including the development of an analysis plan and a series of study specific checklists, in order to prevent or mitigate these offenses. |
format | Online Article Text |
id | pubmed-4401313 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Croatian Society of Medical Biochemistry and Laboratory Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-44013132015-04-24 The misuse and abuse of statistics in biomedical research Thiese, Matthew S. Arnold, Zachary C. Walker, Skyler D. Biochem Med (Zagreb) Review Article Statistics are the primary tools for assessing relationships and evaluating study questions. Unfortunately, these tools are often misused, either inadvertently because of ignorance or lack of planning, or conspicuously to achieve a specified result. Data abuses include the incorrect application of statistical tests, lack of transparency and disclosure about decisions that are made, incomplete or incorrect multivariate model building, or exclusion of outliers. Individually, each of these actions may completely invalidate a study, and often studies are victim to more than one offense. Increasingly there are tools and guidance for researchers to look to, including the development of an analysis plan and a series of study specific checklists, in order to prevent or mitigate these offenses. Croatian Society of Medical Biochemistry and Laboratory Medicine 2015-02-15 /pmc/articles/PMC4401313/ /pubmed/25672462 http://dx.doi.org/10.11613/BM.2015.001 Text en |
spellingShingle | Review Article Thiese, Matthew S. Arnold, Zachary C. Walker, Skyler D. The misuse and abuse of statistics in biomedical research |
title | The misuse and abuse of statistics in biomedical research |
title_full | The misuse and abuse of statistics in biomedical research |
title_fullStr | The misuse and abuse of statistics in biomedical research |
title_full_unstemmed | The misuse and abuse of statistics in biomedical research |
title_short | The misuse and abuse of statistics in biomedical research |
title_sort | misuse and abuse of statistics in biomedical research |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401313/ https://www.ncbi.nlm.nih.gov/pubmed/25672462 http://dx.doi.org/10.11613/BM.2015.001 |
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