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Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

Here we report the crystal structures of the Thermus thermophilus ribosome at 2.3-2.5Å-resolution, which have enabled a comprehensive modeling of rRNA modifications. The structures reveal contacts of modified nucleotides with mRNA and tRNAs or protein pY, and contacts within the ribosome interior st...

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Detalles Bibliográficos
Autores principales:	Polikanov, Yury S., Melnikov, Sergey V., Söll, Dieter, Steitz, Thomas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401423/ https://www.ncbi.nlm.nih.gov/pubmed/25775268 http://dx.doi.org/10.1038/nsmb.2992

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