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Specific Depletion of Ly6C(hi) Inflammatory Monocytes Prevents Immunopathology in Experimental Cerebral Malaria
Plasmodium berghei ANKA (PbA) infection of C57BL/6 mice leads to experimental cerebral malaria (ECM) that is commonly associated with serious T cell mediated damage. In other parasitic infection models, inflammatory monocytes have been shown to regulate Th1 responses but their role in ECM remains po...
Autores principales: | Schumak, Beatrix, Klocke, Katrin, Kuepper, Janina M., Biswas, Aindrila, Djie-Maletz, Andrea, Limmer, Andreas, van Rooijen, Nico, Mack, Matthias, Hoerauf, Achim, Dunay, Ildiko Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401438/ https://www.ncbi.nlm.nih.gov/pubmed/25884830 http://dx.doi.org/10.1371/journal.pone.0124080 |
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