Cargando…

The 15kDa Selenoprotein and Thioredoxin Reductase 1 Promote Colon Cancer by Different Pathways

Selenoproteins mediate much of the cancer-preventive properties of the essential nutrient selenium, but some of these proteins have been shown to also have cancer-promoting effects. We examined the contributions of the 15kDa selenoprotein (Sep15) and thioredoxin reductase 1 (TR1) to cancer developme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsuji, Petra A., Carlson, Bradley A., Yoo, Min-Hyuk, Naranjo-Suarez, Salvador, Xu, Xue-Ming, He, Yiwen, Asaki, Esther, Seifried, Harold E., Reinhold, William C., Davis, Cindy D., Gladyshev, Vadim N., Hatfield, Dolph L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401539/ https://www.ncbi.nlm.nih.gov/pubmed/25886253 http://dx.doi.org/10.1371/journal.pone.0124487

Ejemplares similares

Knockout of the 15 kDa Selenoprotein Protects against Chemically-Induced Aberrant Crypt Formation in Mice
por: Tsuji, Petra A., et al.
Publicado: (2012)

HIF-Independent Regulation of Thioredoxin Reductase 1 Contributes to the High Levels of Reactive Oxygen Species Induced by Hypoxia
por: Naranjo-Suarez, Salvador, et al.
Publicado: (2012)

Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity
por: Canter, Jessica A., et al.
Publicado: (2021)

Deficiency in the 15 kDa Selenoprotein Inhibits Human Colon Cancer Cell Growth
por: Tsuji, Petra A., et al.
Publicado: (2011)

Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells
por: Bang, Jeyoung, et al.
Publicado: (2015)

Mouse Models Targeting Selenocysteine tRNA Expression for Elucidating the Role of Selenoproteins in Health and Development
por: Carlson, Bradley A., et al.
Publicado: (2009)

Targeting Thioredoxin Reductase 1 Reduction in Cancer Cells Inhibits Self-Sufficient Growth and DNA Replication
por: Yoo, Min-Hyuk, et al.
Publicado: (2007)

Historical Roles of Selenium and Selenoproteins in Health and Development: The Good, the Bad and the Ugly
por: Tsuji, Petra A., et al.
Publicado: (2021)

Abrogated Thioredoxin System Causes Increased Sensitivity to TNF-α-Induced Apoptosis via Enrichment of p-ERK 1/2 in the Nucleus
por: Yoo, Min-Hyuk, et al.
Publicado: (2013)

Dietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice
por: Tsuji, Petra A., et al.
Publicado: (2015)

UGA codon position-dependent incorporation of selenocysteine into mammalian selenoproteins
por: Turanov, Anton A., et al.
Publicado: (2013)

Selenoproteins Are Essential for Proper Keratinocyte Function and Skin Development
por: Sengupta, Aniruddha, et al.
Publicado: (2010)

Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression
por: Carlson, Bradley A, et al.
Publicado: (2009)

Delivery of the selenoprotein thioredoxin reductase 1 to mammalian cells
por: Wright, David E., et al.
Publicado: (2022)

Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone
por: Shu, Nan, et al.
Publicado: (2019)

Exposure to Silver Nanoparticles Inhibits Selenoprotein Synthesis and the Activity of Thioredoxin Reductase
por: Srivastava, Milan, et al.
Publicado: (2011)

MITF Is Regulated by Redox Signals Controlled by the Selenoprotein Thioredoxin Reductase 1
por: Kline, Chelsey D., et al.
Publicado: (2022)

DnaJB6: an indirect interaction protein of 15-kDa selenoprotein
por: Tian, Jing, et al.
Publicado: (2012)

Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine
por: Turanov, Anton A., et al.
Publicado: (2015)

Structural Analysis of Glutaredoxin Domain of Mus musculus Thioredoxin Glutathione Reductase
por: Dobrovolska, Olena, et al.
Publicado: (2012)

Polymorphisms in Thioredoxin Reductase and Selenoprotein K Genes and Selenium Status Modulate Risk of Prostate Cancer
por: Méplan, Catherine, et al.
Publicado: (2012)

Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus
por: Fata, Francesca, et al.
Publicado: (2022)

Editorial: Small molecule inhibitors targeting mammalian selenoprotein thioredoxin reductases (TXNRDs): Interactions, mechanisms, and applications
por: Xu, Jianqiang, et al.
Publicado: (2023)

Pathogenic Variants in Selenoproteins and Selenocysteine Biosynthesis Machinery
por: Santesmasses, Didac, et al.
Publicado: (2021)

Cerebellar Hypoplasia in Mice Lacking Selenoprotein Biosynthesis in Neurons
por: Wirth, Eva K., et al.
Publicado: (2014)

Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy
por: Tobe, Ryuta, et al.
Publicado: (2015)

Identification of Thioredoxin Glutathione Reductase Inhibitors That Kill Cestode and Trematode Parasites
por: Ross, Fabiana, et al.
Publicado: (2012)

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation
por: Ouali, Boimpoundi Eunice Flavie, et al.
Publicado: (2020)

Reduced reliance on the trace element selenium during evolution of mammals
por: Lobanov, Alexey V, et al.
Publicado: (2008)

Selenium and Selenoprotein Deficiencies Induce Widespread Pyogranuloma Formation in Mice, while High Levels of Dietary Selenium Decrease Liver Tumor Size Driven by TGFα
por: Moustafa, Mohamed E., et al.
Publicado: (2013)

Adaptive Thermogenesis in a Mouse Model Lacking Selenoprotein Biosynthesis in Brown Adipocytes
por: Seale, Lucia A., et al.
Publicado: (2021)

Initial Step of Selenite Reduction via Thioredoxin for Bacterial Selenoprotein Biosynthesis
por: Shimizu, Atsuki, et al.
Publicado: (2021)

SECIS elements in the coding regions of selenoprotein transcripts are functional in higher eukaryotes
por: Mix, Heiko, et al.
Publicado: (2007)

Data on physicochemical properties of LPEI 25 kDa, PEI“Max” 40 kDa and PEIpro™
por: Delafosse, Laurence, et al.
Publicado: (2016)

Thioredoxin Reductase and its Inhibitors
por: Saccoccia, Fulvio, et al.
Publicado: (2014)

In silico identification of genes involved in selenium metabolism: evidence for a third selenium utilization trait
por: Zhang, Yan, et al.
Publicado: (2008)

In Vitro Inhibition of Angiogenesis by Antibodies Directed against the 37kDa/67kDa Laminin Receptor
por: Khusal, Raksha, et al.
Publicado: (2013)

SECISearch3 and Seblastian: new tools for prediction of SECIS elements and selenoproteins
por: Mariotti, Marco, et al.
Publicado: (2013)

A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer: our experience in thyroid surgery
por: Metere, Alessio, et al.
Publicado: (2018)

Expression of the 60 kDa and 71 kDa heat shock proteins and presence of antibodies against the 71 kDa heat shock protein in pediatric patients with immune thrombocytopenic purpura
por: Xiao, Chengfeng, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_qk26pomemci0omps77ln9cn4kk