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Trypanosomiasis-Induced Megacolon Illustrates How Myenteric Neurons Modulate the Risk for Colon Cancer in Rats and Humans

BACKGROUND: Trypanosomiasis induces a remarkable myenteric neuronal degeneration leading to megacolon. Very little is known about the risk for colon cancer in chagasic megacolon patients. To clarify whether chagasic megacolon impacts on colon carcinogenesis, we investigated the risk for colon cancer...

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Detalles Bibliográficos
Autores principales: Kannen, Vinicius, de Oliveira, Enio C., Motta, Bruno Zene, Chaguri, Annuar Jose, Brunaldi, Mariângela Ottoboni, Garcia, Sérgio B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401552/
https://www.ncbi.nlm.nih.gov/pubmed/25884710
http://dx.doi.org/10.1371/journal.pntd.0003744