Cargando…

EMAST Is Associated with a Poor Prognosis in Microsatellite Instable Metastatic Colorectal Cancer

PURPOSE: To determine the frequency and prognostic value of elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) in metastatic colorectal cancer (mCRC) patients in relation to microsatellite instability (MSI) status and MSH3 protein expression. MATERIAL AND METHODS: The fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Venderbosch, Sabine, van Lent—van Vliet, Shannon, de Haan, Anton F. J., Ligtenberg, Marjolijn J., Goossens, Monique, Punt, Cornelis J. A., Koopman, Miriam, Nagtegaal, Iris D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401564/ https://www.ncbi.nlm.nih.gov/pubmed/25884216 http://dx.doi.org/10.1371/journal.pone.0124538

Ejemplares similares

Mitochondrial microsatellite instability in patients with metastatic colorectal cancer
por: Venderbosch, S., et al.
Publicado: (2015)

Relationship of EMAST and Microsatellite Instability Among Patients with Rectal Cancer
por: Devaraj, Bikash, et al.
Publicado: (2010)

EMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer Progression
por: Carethers, John M., et al.
Publicado: (2015)

Elevated microsatellite instability at selected tetranucleotide (EMAST) repeats in gastric cancer: a distinct microsatellite instability type with potential clinical impact?
por: Herz, Anna‐Lina, et al.
Publicado: (2022)

Microsatellite instability in noncolorectal and nonendometrial malignancies in patients with Lynch syndrome
por: Elze, Lisa, et al.
Publicado: (2023)

EMAST Type of Microsatellite Instability—A Distinct Entity or Blurred Overlap between Stable and MSI Tumors
por: Vuković Đerfi, Kristina, et al.
Publicado: (2023)

Microsatellite instability in rectal cancer: what does it mean? A study of two randomized trials and a systematic review of the literature
por: Swets, Marloes, et al.
Publicado: (2022)

MicroRNA-143 is a putative predictive factor for the response to fluoropyrimidine-based chemotherapy in patients with metastatic colorectal cancer
por: Simmer, Femke, et al.
Publicado: (2015)

High expression of Snail1 is associated with EMAST and poor prognosis in CRC patients
por: Mohammadpour, Somayeh, et al.
Publicado: (2019)

Opportunities for immunotherapy in microsatellite instable colorectal cancer
por: Westdorp, Harm, et al.
Publicado: (2016)

High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue
por: Tol, Jolien, et al.
Publicado: (2010)

Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer
por: Overbeek, L I H, et al.
Publicado: (2007)

Prognosis of mucinous colon cancer is determined by histological biomarkers rather than microsatellite instability
por: van Zwam, Peter H., et al.
Publicado: (2022)

A new method for discovering EMAST sequences in animal models of cancer
por: Bhaskaran, Nitya, et al.
Publicado: (2018)

Comprehensive routine diagnostic screening to identify predictive mutations, gene amplifications, and microsatellite instability in FFPE tumor material
por: Steeghs, Elisabeth M. P., et al.
Publicado: (2020)

Mismatch repair deficiency in early‐onset duodenal, ampullary, and pancreatic carcinomas is a strong indicator for a hereditary defect
por: Kryklyva, Valentyna, et al.
Publicado: (2021)

Very low prevalence of germline MSH6 mutations in hereditary non-polyposis colorectal cancer suspected patients with colorectal cancer without microsatellite instability
por: Kets, C M, et al.
Publicado: (2006)

High expression of ZEB1 is associated with EMAST & metastasis in colorectal cancer patients
por: Mohammadpour, Somayeh, et al.
Publicado: (2022)

The homogeneous mutation status of a 22 gene panel justifies the use of serial sections of colorectal cancer tissue for external quality assessment
por: Dijkstra, Jeroen R., et al.
Publicado: (2015)

Editorial: Microsatellite and microsatellite instability
por: How-Kit, Alexandre, et al.
Publicado: (2023)

Unraveling Neuroendocrine Gallbladder Cancer: Comprehensive Clinicopathologic and Molecular Characterization
por: de Bitter, Tessa J. J., et al.
Publicado: (2021)

The Clinicopathological Features and Genetic Mutations in Gastric Cancer Patients According to EMAST and MSI Status
por: Fang, Wen-Liang, et al.
Publicado: (2020)

Psychological distress in newly diagnosed colorectal cancer patients following microsatellite instability testing for Lynch syndrome on the pathologist’s initiative
por: Landsbergen, K. M., et al.
Publicado: (2012)

Colorectal metastasis to the gallbladder mimicking a primary gallbladder malignancy: histopathological and molecular characteristics
por: de Bitter, Tessa J J, et al.
Publicado: (2019)

Intra-Tumoral Genomic Heterogeneity in Rectal Cancer: Mutational Status Is Dependent on Preoperative Biopsy Depth and Location
por: Vuijk, Floris A., et al.
Publicado: (2021)

MSH3-Deficiency Initiates EMAST without Oncogenic Transformation of Human Colon Epithelial Cells
por: Campregher, Christoph, et al.
Publicado: (2012)

Elevated Microsatellite Alterations at Selected Tetranucleotides (EMAST) Is Not Attributed to MSH3 Loss in Stage I-III Colon cancer: An Automated, Digitalized Assessment by Immunohistochemistry of Whole Slides and Hot Spots()()
por: Watson, Martin M, et al.
Publicado: (2019)

Microsatellite instability in ovarian neoplasms.
por: King, B. L., et al.
Publicado: (1995)

Prognostic Value of Resection of Primary Tumor in Patients with Stage IV Colorectal Cancer: Retrospective Analysis of Two Randomized Studies and a Review of the Literature
por: Venderbosch, Sabine, et al.
Publicado: (2011)

Beyond KRAS mutation status: influence of KRAS copy number status and microRNAs on clinical outcome to cetuximab in metastatic colorectal cancer patients
por: Mekenkamp, Leonie JM, et al.
Publicado: (2012)

Efficacy of Adjuvant 5-Fluorouracil Therapy for Patients with EMAST-Positive Stage II/III Colorectal Cancer
por: Hamaya, Yasushi, et al.
Publicado: (2015)

Infrequent microsatellite instability in oesophageal cancers.
por: Muzeau, F., et al.
Publicado: (1997)

Microsatellite instability in human prostate cancer.
por: Watanabe, M., et al.
Publicado: (1995)

Microsatellite Instability in Sarcoma: Fact or Fiction?
por: Monument, Michael J., et al.
Publicado: (2012)

Characterizing Microsatellite Instability and Chromosome Instability in Interval Colorectal Cancers
por: Cisyk, Amy L., et al.
Publicado: (2018)

Pembrolizumab in Asian patients with microsatellite‐instability‐high/mismatch‐repair‐deficient colorectal cancer
por: Yoshino, Takayuki, et al.
Publicado: (2022)

Highlights from the seventh European Multidisciplinary Colorectal Cancer Congress (EMCCC) 2014
por: Punt, Cornelis JA, et al.
Publicado: (2015)

Microsatellite instability in colorectal cancer
por: Horvat, Matej, et al.
Publicado: (2011)

Microsatellite instability in colorectal cancer
por: Nojadeh, Jafar Nouri, et al.
Publicado: (2018)

Microsatellite instability in colorectal cancer
por: Gian, Luigi de’Angelis, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_lh6bl75spvfk2459auhqk9alud