Cargando…
β-Lactam formation by a non-ribosomal peptide synthetase during antibiotic biosynthesis
Non-ribosomal peptide synthetases (NRPSs) are giant enzymes comprised of modules that house repeated sets of functional domains, which select, activate and couple amino acids drawn from a pool of nearly 500 potential building blocks.(1) The structurally and stereochemically diverse peptides generate...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401618/ https://www.ncbi.nlm.nih.gov/pubmed/25624104 http://dx.doi.org/10.1038/nature14100 |