A Recombinant Vesicular Stomatitis Virus-Based Lassa Fever Vaccine Protects Guinea Pigs and Macaques against Challenge with Geographically and Genetically Distinct Lassa Viruses

BACKGROUND: Lassa virus (LASV) is endemic in several West African countries and is the etiological agent of Lassa fever. Despite the high annual incidence and significant morbidity and mortality rates, currently there are no approved vaccines to prevent infection or disease in humans. Genetically, L...

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Detalles Bibliográficos
Autores principales: Safronetz, David, Mire, Chad, Rosenke, Kyle, Feldmann, Friederike, Haddock, Elaine, Geisbert, Thomas, Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401668/
https://www.ncbi.nlm.nih.gov/pubmed/25884628
http://dx.doi.org/10.1371/journal.pntd.0003736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401668/
https://www.ncbi.nlm.nih.gov/pubmed/25884628
http://dx.doi.org/10.1371/journal.pntd.0003736

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