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The Crystal Structure of D-Threonine Aldolase from Alcaligenes xylosoxidans Provides Insight into a Metal Ion Assisted PLP-Dependent Mechanism

Threonine aldolases catalyze the pyridoxal phosphate (PLP) dependent cleavage of threonine into glycine and acetaldehyde and play a major role in the degradation of this amino acid. In nature, L- as well as D-specific enzymes have been identified, but the exact physiological function of D-threonine...

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Detalles Bibliográficos
Autores principales: Uhl, Michael K., Oberdorfer, Gustav, Steinkellner, Georg, Riegler-Berket, Lina, Mink, Daniel, van Assema, Friso, Schürmann, Martin, Gruber, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401734/
https://www.ncbi.nlm.nih.gov/pubmed/25884707
http://dx.doi.org/10.1371/journal.pone.0124056