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The Crystal Structure of D-Threonine Aldolase from Alcaligenes xylosoxidans Provides Insight into a Metal Ion Assisted PLP-Dependent Mechanism
Threonine aldolases catalyze the pyridoxal phosphate (PLP) dependent cleavage of threonine into glycine and acetaldehyde and play a major role in the degradation of this amino acid. In nature, L- as well as D-specific enzymes have been identified, but the exact physiological function of D-threonine...
Autores principales: | Uhl, Michael K., Oberdorfer, Gustav, Steinkellner, Georg, Riegler-Berket, Lina, Mink, Daniel, van Assema, Friso, Schürmann, Martin, Gruber, Karl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401734/ https://www.ncbi.nlm.nih.gov/pubmed/25884707 http://dx.doi.org/10.1371/journal.pone.0124056 |
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