Transgenically expressed Parascaris P-glycoprotein-11 can modulate ivermectin susceptibility in Caenorhabditis elegans

P-glycoproteins (Pgps) are suspected to mediate drug extrusion in nematodes contributing to macrocyclic lactone resistance. This association was recently shown for Parascaris Pgp-11. Ivermectin resistance was correlated with the presence of three pgp-11 single nucleotide polymorphisms and/or increas...

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Detalles Bibliográficos
Autores principales: Janssen, I. Jana I., Krücken, Jürgen, Demeler, Janina, von Samson-Himmelstjerna, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401813/
https://www.ncbi.nlm.nih.gov/pubmed/25905032
http://dx.doi.org/10.1016/j.ijpddr.2015.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401813/
https://www.ncbi.nlm.nih.gov/pubmed/25905032
http://dx.doi.org/10.1016/j.ijpddr.2015.03.003

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