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Attention and normalization circuits in macaque V1

Attention affects neuronal processing and improves behavioural performance. In extrastriate visual cortex these effects have been explained by normalization models, which assume that attention influences the circuit that mediates surround suppression. While normalization models have been able to exp...

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Detalles Bibliográficos
Autores principales: Sanayei, M, Herrero, J L, Distler, C, Thiele, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402004/
https://www.ncbi.nlm.nih.gov/pubmed/25757941
http://dx.doi.org/10.1111/ejn.12857
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author Sanayei, M
Herrero, J L
Distler, C
Thiele, A
author_facet Sanayei, M
Herrero, J L
Distler, C
Thiele, A
author_sort Sanayei, M
collection PubMed
description Attention affects neuronal processing and improves behavioural performance. In extrastriate visual cortex these effects have been explained by normalization models, which assume that attention influences the circuit that mediates surround suppression. While normalization models have been able to explain attentional effects, their validity has rarely been tested against alternative models. Here we investigate how attention and surround/mask stimuli affect neuronal firing rates and orientation tuning in macaque V1. Surround/mask stimuli provide an estimate to what extent V1 neurons are affected by normalization, which was compared against effects of spatial top down attention. For some attention/surround effect comparisons, the strength of attentional modulation was correlated with the strength of surround modulation, suggesting that attention and surround/mask stimulation (i.e. normalization) might use a common mechanism. To explore this in detail, we fitted multiplicative and additive models of attention to our data. In one class of models, attention contributed to normalization mechanisms, whereas in a different class of models it did not. Model selection based on Akaike's and on Bayesian information criteria demonstrated that in most cells the effects of attention were best described by models where attention did not contribute to normalization mechanisms. This demonstrates that attentional influences on neuronal responses in primary visual cortex often bypass normalization mechanisms.
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spelling pubmed-44020042015-04-22 Attention and normalization circuits in macaque V1 Sanayei, M Herrero, J L Distler, C Thiele, A Eur J Neurosci Cognitive Neuroscience Attention affects neuronal processing and improves behavioural performance. In extrastriate visual cortex these effects have been explained by normalization models, which assume that attention influences the circuit that mediates surround suppression. While normalization models have been able to explain attentional effects, their validity has rarely been tested against alternative models. Here we investigate how attention and surround/mask stimuli affect neuronal firing rates and orientation tuning in macaque V1. Surround/mask stimuli provide an estimate to what extent V1 neurons are affected by normalization, which was compared against effects of spatial top down attention. For some attention/surround effect comparisons, the strength of attentional modulation was correlated with the strength of surround modulation, suggesting that attention and surround/mask stimulation (i.e. normalization) might use a common mechanism. To explore this in detail, we fitted multiplicative and additive models of attention to our data. In one class of models, attention contributed to normalization mechanisms, whereas in a different class of models it did not. Model selection based on Akaike's and on Bayesian information criteria demonstrated that in most cells the effects of attention were best described by models where attention did not contribute to normalization mechanisms. This demonstrates that attentional influences on neuronal responses in primary visual cortex often bypass normalization mechanisms. BlackWell Publishing Ltd 2015-04 2015-03-11 /pmc/articles/PMC4402004/ /pubmed/25757941 http://dx.doi.org/10.1111/ejn.12857 Text en © 2015 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cognitive Neuroscience
Sanayei, M
Herrero, J L
Distler, C
Thiele, A
Attention and normalization circuits in macaque V1
title Attention and normalization circuits in macaque V1
title_full Attention and normalization circuits in macaque V1
title_fullStr Attention and normalization circuits in macaque V1
title_full_unstemmed Attention and normalization circuits in macaque V1
title_short Attention and normalization circuits in macaque V1
title_sort attention and normalization circuits in macaque v1
topic Cognitive Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402004/
https://www.ncbi.nlm.nih.gov/pubmed/25757941
http://dx.doi.org/10.1111/ejn.12857
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