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Progressive decline of glucocerebrosidase in aging and Parkinson's disease
The principal risk factor for developing most adult onset neurodegenerative diseases is aging, with incidence rising significantly after age 50. Despite research efforts, the causes of Parkinson's disease (PD) remain unknown. As neurons age, they show signs of diminished lysosomal and mitochond...
Autores principales: | Rocha, Emily M, Smith, Gaynor A, Park, Eric, Cao, Hongmei, Brown, Eilish, Hallett, Penelope, Isacson, Ole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402088/ https://www.ncbi.nlm.nih.gov/pubmed/25909088 http://dx.doi.org/10.1002/acn3.177 |
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