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Monitoring methionine sulfoxide with stereospecific mechanism-based fluorescent sensors

Methionine can be reversibly oxidized to methionine sulfoxide (MetO) under physiological and pathophysiological conditions, but its use as a redox marker suffers from the lack of tools to detect and quantify MetO within cells. In this work, we created a pair of complementary stereospecific genetical...

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Detalles Bibliográficos
Autores principales: Tarrago, Lionel, Péterfi, Zalán, Lee, Byung Cheon, Michel, Thomas, Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402147/
https://www.ncbi.nlm.nih.gov/pubmed/25799144
http://dx.doi.org/10.1038/nchembio.1787