Muscle Extracellular Matrix Scaffold Is a Multipotent Environment

The multipotency of scaffolds is a new concept. Skeletal muscle acellular scaffolds (MAS) implanted at the interface of Tibialis Anterior/tibial bone and masseter muscle/mandible bone in a murine model were colonized by muscle cells near the host muscle and by bone-cartilaginous tissues near the hos...

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Autores principales: Aulino, Paola, Costa, Alessandra, Chiaravalloti, Ernesto, Perniconi, Barbara, Adamo, Sergio, Coletti, Dario, Marrelli, Massimo, Tatullo, Marco, Teodori, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Short Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402437/
https://www.ncbi.nlm.nih.gov/pubmed/25897295
http://dx.doi.org/10.7150/ijms.10761
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author Aulino, Paola
Costa, Alessandra
Chiaravalloti, Ernesto
Perniconi, Barbara
Adamo, Sergio
Coletti, Dario
Marrelli, Massimo
Tatullo, Marco
Teodori, Laura
author_facet Aulino, Paola
Costa, Alessandra
Chiaravalloti, Ernesto
Perniconi, Barbara
Adamo, Sergio
Coletti, Dario
Marrelli, Massimo
Tatullo, Marco
Teodori, Laura
author_sort Aulino, Paola
collection PubMed
description The multipotency of scaffolds is a new concept. Skeletal muscle acellular scaffolds (MAS) implanted at the interface of Tibialis Anterior/tibial bone and masseter muscle/mandible bone in a murine model were colonized by muscle cells near the host muscle and by bone-cartilaginous tissues near the host bone, thus highlighting the importance of the environment in directing cell homing and differentiation. These results unveil the multipotency of MAS and point to the potential of this new technique as a valuable tool in musculo-skeletal tissue regeneration.
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spelling pubmed-44024372015-04-20 Muscle Extracellular Matrix Scaffold Is a Multipotent Environment Aulino, Paola Costa, Alessandra Chiaravalloti, Ernesto Perniconi, Barbara Adamo, Sergio Coletti, Dario Marrelli, Massimo Tatullo, Marco Teodori, Laura Int J Med Sci Short Research Communication The multipotency of scaffolds is a new concept. Skeletal muscle acellular scaffolds (MAS) implanted at the interface of Tibialis Anterior/tibial bone and masseter muscle/mandible bone in a murine model were colonized by muscle cells near the host muscle and by bone-cartilaginous tissues near the host bone, thus highlighting the importance of the environment in directing cell homing and differentiation. These results unveil the multipotency of MAS and point to the potential of this new technique as a valuable tool in musculo-skeletal tissue regeneration. Ivyspring International Publisher 2015-04-06 /pmc/articles/PMC4402437/ /pubmed/25897295 http://dx.doi.org/10.7150/ijms.10761 Text en © 2015 Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. See http://ivyspring.com/terms for terms and conditions.
spellingShingle Short Research Communication
Aulino, Paola
Costa, Alessandra
Chiaravalloti, Ernesto
Perniconi, Barbara
Adamo, Sergio
Coletti, Dario
Marrelli, Massimo
Tatullo, Marco
Teodori, Laura
Muscle Extracellular Matrix Scaffold Is a Multipotent Environment
title Muscle Extracellular Matrix Scaffold Is a Multipotent Environment
title_full Muscle Extracellular Matrix Scaffold Is a Multipotent Environment
title_fullStr Muscle Extracellular Matrix Scaffold Is a Multipotent Environment
title_full_unstemmed Muscle Extracellular Matrix Scaffold Is a Multipotent Environment
title_short Muscle Extracellular Matrix Scaffold Is a Multipotent Environment
title_sort muscle extracellular matrix scaffold is a multipotent environment
topic Short Research Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402437/
https://www.ncbi.nlm.nih.gov/pubmed/25897295
http://dx.doi.org/10.7150/ijms.10761
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