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An ensemble strategy that significantly improves de novo assembly of microbial genomes from metagenomic next-generation sequencing data
Next-generation sequencing (NGS) approaches rapidly produce millions to billions of short reads, which allow pathogen detection and discovery in human clinical, animal and environmental samples. A major limitation of sequence homology-based identification for highly divergent microorganisms is the s...
Autores principales: | Deng, Xutao, Naccache, Samia N., Ng, Terry, Federman, Scot, Li, Linlin, Chiu, Charles Y., Delwart, Eric L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402509/ https://www.ncbi.nlm.nih.gov/pubmed/25586223 http://dx.doi.org/10.1093/nar/gkv002 |
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