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Identification of U2AF(35)-dependent exons by RNA-Seq reveals a link between 3′ splice-site organization and activity of U2AF-related proteins

The auxiliary factor of U2 small nuclear RNA (U2AF) is a heterodimer consisting of 65- and 35-kD proteins that bind the polypyrimidine tract (PPT) and AG dinucleotides at the 3′ splice site (3′ss). The gene encoding U2AF35 (U2AF1) is alternatively spliced, giving rise to two isoforms U2AF35a and U2A...

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Detalles Bibliográficos
Autores principales:	Kralovicova, Jana, Knut, Marcin, Cross, Nicholas C. P., Vorechovsky, Igor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402522/ https://www.ncbi.nlm.nih.gov/pubmed/25779042 http://dx.doi.org/10.1093/nar/gkv194

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