Cargando…

Srs2 promotes Mus81–Mms4-mediated resolution of recombination intermediates

A variety of DNA lesions, secondary DNA structures or topological stress within the DNA template may lead to stalling of the replication fork. Recovery of such forks is essential for the maintenance of genomic stability. The structure-specific endonuclease Mus81–Mms4 has been implicated in processin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chavdarova, Melita, Marini, Victoria, Sisakova, Alexandra, Sedlackova, Hana, Vigasova, Dana, Brill, Steven J., Lisby, Michael, Krejci, Lumir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402524/ https://www.ncbi.nlm.nih.gov/pubmed/25765656 http://dx.doi.org/10.1093/nar/gkv198

Ejemplares similares

Cooperativity of Mus81·Mms4 with Rad54 in the Resolution of Recombination and Replication Intermediates
por: Matulova, Petra, et al.
Publicado: (2009)

Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains
por: Sebesta, Marek, et al.
Publicado: (2017)

Cell cycle-dependent regulation of the nuclease activity of Mus81–Eme1/Mms4
por: Gallo-Fernández, María, et al.
Publicado: (2012)

Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage
por: Saugar, Irene, et al.
Publicado: (2013)

A winged helix domain in human MUS81 binds DNA and modulates the endonuclease activity of MUS81 complexes
por: Fadden, Andrew J., et al.
Publicado: (2013)

Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
por: Kolesar, Peter, et al.
Publicado: (2012)

Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association
por: Sarangi, Prabha, et al.
Publicado: (2014)

Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair
por: Larin, Meghan, et al.
Publicado: (2014)

Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption
por: Colavito, Sierra, et al.
Publicado: (2009)

Srs2 and Mus81–Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates
por: Keyamura, Kenji, et al.
Publicado: (2016)

Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress
por: Palma, Anita, et al.
Publicado: (2018)

Phosphorylation status of MUS81 is a modifier of Olaparib sensitivity in BRCA2-deficient cells
por: Blandino, Francesca, et al.
Publicado: (2023)

Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein
por: Benitez, Anaid, et al.
Publicado: (2014)

The nuclease FAN1 is involved in DNA crosslink repair in Arabidopsis thaliana independently of the nuclease MUS81
por: Herrmann, Natalie J., et al.
Publicado: (2015)

A physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repair
por: Thu, Huong Phung Thi, et al.
Publicado: (2015)

Lif1 SUMOylation and its role in non-homologous end-joining
por: Vigasova, Dana, et al.
Publicado: (2013)

Role of PCNA and RFC in promoting Mus81-complex activity
por: Sisakova, Alexandra, et al.
Publicado: (2017)

The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant
por: Lorenz, Alexander, et al.
Publicado: (2010)

Mus81 nuclease and Sgs1 helicase are essential for meiotic recombination in a protist lacking a synaptonemal complex
por: Lukaszewicz, Agnieszka, et al.
Publicado: (2013)

RAD51 and mitotic function of mus81 are essential for recovery from low-dose of camptothecin in the absence of the WRN exonuclease
por: Aiello, Francesca Antonella, et al.
Publicado: (2019)

Single-molecule visualization of human RECQ5 interactions with single-stranded DNA recombination intermediates
por: Xue, Chaoyou, et al.
Publicado: (2020)

Rad52 SUMOylation affects the efficiency of the DNA repair
por: Altmannova, Veronika, et al.
Publicado: (2010)

Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability
por: Wanzek, Katharina, et al.
Publicado: (2017)

Strand invasion by HLTF as a mechanism for template switch in fork rescue
por: Burkovics, Peter, et al.
Publicado: (2014)

The structure and DNA-binding properties of Mgm101 from a yeast with a linear mitochondrial genome
por: Pevala, Vladimír, et al.
Publicado: (2016)

Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats
por: Nguyen, Jennifer H.G., et al.
Publicado: (2017)

Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state
por: Špírek, Mário, et al.
Publicado: (2018)

A structure–function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance
por: Shemesh, Keren, et al.
Publicado: (2017)

Rad51 gain-of-function mutants that exhibit high affinity DNA binding cause DNA damage sensitivity in the absence of Srs2
por: Malik, Punjab S., et al.
Publicado: (2008)

The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis
por: Burkovics, Peter, et al.
Publicado: (2016)

Involvement of Schizosaccharomyces pombe rrp1(+) and rrp2(+) in the Srs2- and Swi5/Sfr1-dependent pathway in response to DNA damage and replication inhibition
por: Dziadkowiec, Dorota, et al.
Publicado: (2013)

DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs
por: Stefanovie, Barbora, et al.
Publicado: (2020)

Genetic and functional interactions between Mus81–Mms4 and Rad27
por: Kang, Min-Jung, et al.
Publicado: (2010)

MUS81 cleaves TOP1-derived lesions and other DNA–protein cross-links
por: Marini, Victoria, et al.
Publicado: (2023)

Length-dependent processing of telomeres in the absence of telomerase
por: Fallet, Emilie, et al.
Publicado: (2014)

Regulation of telomere metabolism by the RNA processing protein Xrn1
por: Cesena, Daniele, et al.
Publicado: (2017)

A distinct role for recombination repair factors in an early cellular response to transcription–replication conflicts
por: Shao, Xin, et al.
Publicado: (2020)

DNA intermediates of meiotic recombination in synchronous S. pombe at optimal temperature
por: Hyppa, Randy W., et al.
Publicado: (2014)

Genomic landscape of single-stranded DNA gapped intermediates in Escherichia coli
por: Pham, Phuong, et al.
Publicado: (2021)

Rad53 regulates the lifetime of Rdh54 at homologous recombination intermediates
por: Hu, Jingyi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1bksk2gu2ggobnip2khuqu6vtt