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Assessing the limits of restraint-based 3D modeling of genomes and genomic domains

Restraint-based modeling of genomes has been recently explored with the advent of Chromosome Conformation Capture (3C-based) experiments. We previously developed a reconstruction method to resolve the 3D architecture of both prokaryotic and eukaryotic genomes using 3C-based data. These models were c...

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Detalles Bibliográficos
Autores principales: Trussart, Marie, Serra, François, Baù, Davide, Junier, Ivan, Serrano, Luís, Marti-Renom, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402535/
https://www.ncbi.nlm.nih.gov/pubmed/25800747
http://dx.doi.org/10.1093/nar/gkv221