New insights into Hoogsteen base pairs in DNA duplexes from a structure-based survey

Hoogsteen (HG) base pairs (bps) provide an alternative pairing geometry to Watson–Crick (WC) bps and can play unique functional roles in duplex DNA. Here, we use structural features unique to HG bps (syn purine base, HG hydrogen bonds and constricted C1′–C1′ distance across the bp) to search for HG...

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Detalles Bibliográficos
Autores principales: Zhou, Huiqing, Hintze, Bradley J., Kimsey, Isaac J., Sathyamoorthy, Bharathwaj, Yang, Shan, Richardson, Jane S., Al-Hashimi, Hashim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402545/
https://www.ncbi.nlm.nih.gov/pubmed/25813047
http://dx.doi.org/10.1093/nar/gkv241

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