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Triptolide-Mediated Apoptosis by Suppression of Focal Adhesion Kinase through Extrinsic and Intrinsic Pathways in Human Melanoma Cells

Triptolide (TPL) has been shown to inhibit cell proliferation and induce apoptosis in various human cancer cells; however, the precise mechanism of apoptosis induced by TPL in human melanoma cells has not yet been elucidated. In this study, we investigated the precise mechanism underlying cytocidal...

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Detalles Bibliográficos
Autores principales: Kwon, Haw-Young, Kim, Kyoung-Sook, Baik, Ji-Sue, Moon, Hyung-In, Lee, Ji-Won, Kim, Cheorl-Ho, Cho, Young-Su, Jeong, Yong-Kee, Lee, Young-Choon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402567/
https://www.ncbi.nlm.nih.gov/pubmed/25945102
http://dx.doi.org/10.1155/2013/172548

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