New Dimeric and seco-Abietane Diterpenoids from Salvia wardii

Two dimeric abietane diterpenoids, salviwardins A and B (1 and 2), and a seco-abietane diterpenoid salviwardin C (3), along with five known analogues (4–8), were isolated from the roots of Salvia wardii. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibit...

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Detalles Bibliográficos
Autores principales: Xiao, Qiu-Li, Xia, Fan, Yang, Xing-Wei, Liao, Yang, Yang, Li-Xin, Wei, Yu-Kun, Li, Xian, Xu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402580/
https://www.ncbi.nlm.nih.gov/pubmed/25850377
http://dx.doi.org/10.1007/s13659-015-0054-6
Descripción
Sumario:Two dimeric abietane diterpenoids, salviwardins A and B (1 and 2), and a seco-abietane diterpenoid salviwardin C (3), along with five known analogues (4–8), were isolated from the roots of Salvia wardii. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibitory activities of these isolates against five human cancer cell lines in vitro were also tested. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-015-0054-6) contains supplementary material, which is available to authorized users.

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