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Identifying overlapping mutated driver pathways by constructing gene networks in cancer

BACKGROUND: Large-scale cancer genomic projects are providing lots of data on genomic, epigenomic and gene expression aberrations in many cancer types. One key challenge is to detect functional driver pathways and to filter out nonfunctional passenger genes in cancer genomics. Vandin et al. introduc...

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Detalles Bibliográficos
Autores principales:	Wu, Hao, Gao, Lin, Li, Feng, Song, Fei, Yang, Xiaofei, Kasabov, Nikola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402595/ https://www.ncbi.nlm.nih.gov/pubmed/25859819 http://dx.doi.org/10.1186/1471-2105-16-S5-S3

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