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Dietary sugar promotes systemic TOR activation in Drosophila through AKH-dependent selective secretion of Dilp3

Secreted ligands of the insulin family promote cell growth and maintain sugar homeostasis. Insulin release is tightly regulated in response to dietary conditions, but how insulin producing cells (IPCs) coordinate their responses to distinct nutrient signals is unclear. Here, we show that regulation...

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Detalles Bibliográficos
Autores principales: Kim, Jung, Neufeld, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402654/
https://www.ncbi.nlm.nih.gov/pubmed/25882208
http://dx.doi.org/10.1038/ncomms7846

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