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How does the Merkel polyomavirus lead to a lethal cancer? Many answers, many questions, and a new mouse model
The Merkel cell polyomavirus (MCPyV), discovered in 2008, drives development of most Merkel cell carcinomas (MCCs) through several canonical mechanisms. A glaring gap in our knowledge remains the basis by which MCPyV, among all 12 human polyomaviruses, is the only one that causes cancer in humans. M...
Autores principales: | Church, Candice, Nghiem, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402710/ https://www.ncbi.nlm.nih.gov/pubmed/25882464 http://dx.doi.org/10.1038/jid.2015.4 |
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