Determination of Anti-Adeno-Associated Virus Vector Neutralizing Antibody Titer with an In Vitro Reporter System

Adeno-associated virus (AAV) vectors are a platform of choice for in vivo gene transfer applications. However, neutralizing antibodies (NAb) to AAV can be found in humans and some animal species as a result of exposure to the wild-type virus, and high-titer NAb develop following AAV vector administr...

Descripción completa

Detalles Bibliográficos
Autores principales: Meliani, Amine, Leborgne, Christian, Triffault, Sabrina, Jeanson-Leh, Laurence, Veron, Philippe, Mingozzi, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403012/
https://www.ncbi.nlm.nih.gov/pubmed/25819687
http://dx.doi.org/10.1089/hgtb.2015.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403012/
https://www.ncbi.nlm.nih.gov/pubmed/25819687
http://dx.doi.org/10.1089/hgtb.2015.037

Ejemplares similares