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Pseudomonas aeruginosa Pyocyanin Induces Neutrophil Death via Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase
Aims: Pulmonary infections with Pseudomonas aeruginosa are a serious clinical problem and are often lethal. Because many strains of P. aeruginosa are resistant to antibiotics, therapeutic options are limited. Neutrophils play an important role in the host's early acute defense against pulmonary...
Autores principales: | Managò, Antonella, Becker, Katrin Anne, Carpinteiro, Alexander, Wilker, Barbara, Soddemann, Matthias, Seitz, Aaron P., Edwards, Michael J., Grassmé, Heike, Szabò, Ildiko, Gulbins, Erich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403017/ https://www.ncbi.nlm.nih.gov/pubmed/25686490 http://dx.doi.org/10.1089/ars.2014.5979 |
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