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Molecular characterization of full-length Tat in HIV-1 subtypes B and C

HIV-1Tat (trans-acting activator of transcription) plays essential roles in the replication through viral mRNA and genome transcription from the HIV-1 LTR promoter. However, Tat undergoes continuous amino acid substitutions. As a consequence, the virus escapes from host immunity indicating that gene...

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Detalles Bibliográficos
Autores principales: Roy, Chandra Nath, Khandaker, Irona, Furuse, Yuki, Oshitani, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403036/
https://www.ncbi.nlm.nih.gov/pubmed/25914449
http://dx.doi.org/10.6026/97320630011151