Targeted Delivery of 5-fluorouracil with Monoclonal Antibody Modified Bovine Serum Albumin Nanoparticles

Herein, 1F2, an anti-HER2 monoclonal antibody (mAb), was covalently coupled to the surface of 5-Fluorouracil (5-FU) loaded bovine serum albumin (BSA) nanoparticles. Concerning two different crosslinkers for conjugation of 1F2, Maleimide-poly (ethylene glycol)-Succinimidyl carbonate (Mal-PEG5000-NHS)...

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Detalles Bibliográficos
Autores principales: Fadaeian, Ghazal, Shojaosadati, Seyed Abbas, Kouchakzadeh, Hasan, Shokri, Fazel, Soleimani, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403055/
https://www.ncbi.nlm.nih.gov/pubmed/25901146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403055/
https://www.ncbi.nlm.nih.gov/pubmed/25901146

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