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Cyclodextrine Screening for the Chiral Separation of Carvedilol by Capillary Electrophoresis

Carvedilol is administered as a racemic mixture of the R(+)- and S(-)-enantiomers, although it was demonstrated that the two enantiomers exhibit different pharmacological effects and stereoselective pharmacokinetics. The aim of this study was the evaluation of several native and derivatized cyclodex...

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Detalles Bibliográficos
Autores principales: Hancu, Gabriel, Cârje, Anca, Iuga, Ileana, Fülöp, Ibolya, Szabó, Zoltán-István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403058/
https://www.ncbi.nlm.nih.gov/pubmed/25901149