Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1

The ETS family transcription factor PU.1 is essential for the development of several blood lineages, including T cells, but its function in intrathymic T-cell precursors has been poorly defined. In the thymus, high PU.1 expression persists through multiple cell divisions in early stages but then fal...

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Detalles Bibliográficos
Autores principales: Champhekar, Ameya, Damle, Sagar S., Freedman, George, Carotta, Sebastian, Nutt, Stephen L., Rothenberg, Ellen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403259/
https://www.ncbi.nlm.nih.gov/pubmed/25846797
http://dx.doi.org/10.1101/gad.259879.115

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