Cargando…
Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences
Repetitive nucleotide or amino acid sequences are often engineered into probes and biosensors to achieve functional readouts and robust signal amplification. However, these repeated sequences are notoriously prone to aberrant deletion and degradation, impacting the ability to correctly detect and in...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403262/ https://www.ncbi.nlm.nih.gov/pubmed/25877922 http://dx.doi.org/10.1101/gad.259358.115 |