Making water-soluble integral membrane proteins in vivo using an amphipathic protein fusion strategy

Integral membrane proteins (IMPs) play crucial roles in all cells and represent attractive pharmacological targets. However, functional and structural studies of IMPs are hindered by their hydrophobic nature and the fact that they are generally unstable following extraction from their native membran...

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Detalles Bibliográficos
Autores principales: Mizrachi, Dario, Chen, Yujie, Liu, Jiayan, Peng, Hwei-Ming, Ke, Ailong, Pollack, Lois, Turner, Raymond J., Auchus, Richard J., DeLisa, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403311/
https://www.ncbi.nlm.nih.gov/pubmed/25851941
http://dx.doi.org/10.1038/ncomms7826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403311/
https://www.ncbi.nlm.nih.gov/pubmed/25851941
http://dx.doi.org/10.1038/ncomms7826

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