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Making water-soluble integral membrane proteins in vivo using an amphipathic protein fusion strategy
Integral membrane proteins (IMPs) play crucial roles in all cells and represent attractive pharmacological targets. However, functional and structural studies of IMPs are hindered by their hydrophobic nature and the fact that they are generally unstable following extraction from their native membran...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403311/ https://www.ncbi.nlm.nih.gov/pubmed/25851941 http://dx.doi.org/10.1038/ncomms7826 |