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A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses
Synaptic plasticity is the cornerstone of processes underlying persistent nociceptive activity-induced changes in normal nociceptive sensitivity. Kalirin-7 is a multifunctional guanine-nucleotide-exchange factor (GEF) for Rho GTPases that is characterized by its localization at excitatory synapses,...
Autores principales: | Lu, Jianning, Luo, Ceng, Bali, Kiran Kumar, Xie, Rou-Gang, Mains, Richard E., Eipper, Betty A., Kuner, Rohini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403379/ https://www.ncbi.nlm.nih.gov/pubmed/25865668 http://dx.doi.org/10.1038/ncomms7820 |
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